Refractory Iron Deficiency Anemia
نویسندگان
چکیده
منابع مشابه
Iron refractory iron deficiency anemia.
Iron refractory iron deficiency anemia is a hereditary recessive anemia due to a defect in the TMPRSS6 gene encoding Matriptase-2. This protein is a transmembrane serine protease that plays an essential role in down-regulating hepcidin, the key regulator of iron homeostasis. Hallmarks of this disease are microcytic hypochromic anemia, low transferrin saturation and normal/high serum hepcidin va...
متن کاملIron-Refractory Iron Deficiency Anemia
Iron is essential for life because it is indispensable for several biological reactions, such as oxygen transport, DNA synthesis, and cell proliferation. Over the past few years, our understanding of iron metabolism and its regulation has changed dramatically. New disorders of iron metabolism have emerged, and the role of iron as a cofactor in other disorders has begun to be recognized. The stu...
متن کاملRefractory anemia with ring sideroblasts masked by iron deficiency anemia.
A 84-year-old woman with a long-standing history of progressive exertional dyspnea and fatigue was assessed for concomitant anemia. She also had coronary artery disease, chronic obstructive pulmonary disease, hypertension, and gout. Her hemoglobin was 109 g/L with a mean corpuscular volume of 76.1 fL and red blood cell distribution width (RDW) at 19.4%. White cell count including differential a...
متن کاملAnemia, Iron Deficiency, and Iron Deficiency Anemia
Anemia is one of the most widespread public health problems, especially in developing countries, and has important health and welfare, social, and economic consequences. These include impaired cognitive development, reduced physical work capacity, and in severe cases increased risk of mortality, particularly during the perinatal period. There is also evidence that anemia may result in reduced g...
متن کاملRefractory iron deficiency anemia and Helicobacter Pylori Infection in pediatrics: A review
Background Since the discovery of Helicobacter pylori, several clinical reports have demonstrated that H. Pylori infection has emerged as a new cause of refractory iron stores in children. We carried out a systematic literature review to primarily evaluate the existing evidence on the association between childhood H. Pylori infection and iron deficiency anemia (IDA) and secondly, to investigat...
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ژورنال
عنوان ژورنال: Current Developments in Nutrition
سال: 2020
ISSN: 2475-2991
DOI: 10.1093/cdn/nzaa067_068